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Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability
BACKGROUND: Factor XIII (FXIII) is an important proenzyme in the hemostatic system. The plasma-derived enzyme activated FXIII cross-links fibrin fibers within thrombi to increase their mechanical strength and cross-links fibrin to fibrinolytic inhibitors, specifically α(2)-antiplasmin, to increase r...
Autores principales: | Mitchell, Joanne L., Little, Gemma, Bye, Alexander P., Gaspar, Renato S., Unsworth, Amanda J., Kriek, Neline, Sage, Tanya, Stainer, Alexander, Sangowawa, Ibidayo, Morrow, Gael B., Bastos, Ricardo N., Shapiro, Susan, Desborough, Michael J.R., Curry, Nicola, Gibbins, Jonathan M., Whyte, Claire S., Mutch, Nicola J., Jones, Christopher I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439398/ https://www.ncbi.nlm.nih.gov/pubmed/37601014 http://dx.doi.org/10.1016/j.rpth.2023.100200 |
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