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Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine
In the structure of the title compound, C(15)H(19)N(3)O(5)S(2), the bond lengths at the linking sulfur atom are significantly different [1.7473 (17) and 1.811 (2) Å], and the angle at the exocyclic nitrogen atom is wide at 128.45 (18)°. The interplanar angle between the tolyl and thiadiazole ring...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439424/ https://www.ncbi.nlm.nih.gov/pubmed/37601574 http://dx.doi.org/10.1107/S2056989023005248 |
| _version_ | 1785092941525549056 |
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| author | Abu-Zaied, Mamdouh A. Hebishy, Ali M. S. Elgemeie, Galal H. Salama, Hagar T. Jones, Peter G. |
| author_facet | Abu-Zaied, Mamdouh A. Hebishy, Ali M. S. Elgemeie, Galal H. Salama, Hagar T. Jones, Peter G. |
| author_sort | Abu-Zaied, Mamdouh A. |
| collection | PubMed |
| description | In the structure of the title compound, C(15)H(19)N(3)O(5)S(2), the bond lengths at the linking sulfur atom are significantly different [1.7473 (17) and 1.811 (2) Å], and the angle at the exocyclic nitrogen atom is wide at 128.45 (18)°. The interplanar angle between the tolyl and thiadiazole rings is 9.2 (1)°. The complex hydrogen-bonding pattern, involving five donors and five acceptors, can be broken down into a one-dimensional ribbon parallel to the b axis, involving hydrogen bonds of the sugar residues only, and a two-dimensional layer structure parallel to the ab plane, based on the N—H⋯O and O—H⋯N hydrogen bonds. |
| format | Online Article Text |
| id | pubmed-10439424 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-104394242023-08-20 Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine Abu-Zaied, Mamdouh A. Hebishy, Ali M. S. Elgemeie, Galal H. Salama, Hagar T. Jones, Peter G. Acta Crystallogr E Crystallogr Commun Research Communications In the structure of the title compound, C(15)H(19)N(3)O(5)S(2), the bond lengths at the linking sulfur atom are significantly different [1.7473 (17) and 1.811 (2) Å], and the angle at the exocyclic nitrogen atom is wide at 128.45 (18)°. The interplanar angle between the tolyl and thiadiazole rings is 9.2 (1)°. The complex hydrogen-bonding pattern, involving five donors and five acceptors, can be broken down into a one-dimensional ribbon parallel to the b axis, involving hydrogen bonds of the sugar residues only, and a two-dimensional layer structure parallel to the ab plane, based on the N—H⋯O and O—H⋯N hydrogen bonds. International Union of Crystallography 2023-06-20 /pmc/articles/PMC10439424/ /pubmed/37601574 http://dx.doi.org/10.1107/S2056989023005248 Text en © Abu-Zaied et al. 2023 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Research Communications Abu-Zaied, Mamdouh A. Hebishy, Ali M. S. Elgemeie, Galal H. Salama, Hagar T. Jones, Peter G. Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine |
| title | Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine |
| title_full | Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine |
| title_fullStr | Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine |
| title_full_unstemmed | Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine |
| title_short | Crystal structure of 5-(β-d-glucopyranosylthio)-N-(4-methylphenyl)-1,3,4-thiadiazol-2-amine |
| title_sort | crystal structure of 5-(β-d-glucopyranosylthio)-n-(4-methylphenyl)-1,3,4-thiadiazol-2-amine |
| topic | Research Communications |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439424/ https://www.ncbi.nlm.nih.gov/pubmed/37601574 http://dx.doi.org/10.1107/S2056989023005248 |
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