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Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults?

BACKGROUND: The effects of COVID-19 on the organism are still being investigated, especially after the transformation of this virus from a respiratory disease in its first appearance to a multi-organ disease that can affect nearly all systems and organs including the endocrinological system. The obj...

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Autores principales: Jabbour, Rose Mary, Hallit, Souheil, Saliby, Rita, Baydoun, Abed El Karim, Nakhoul, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439538/
https://www.ncbi.nlm.nih.gov/pubmed/37596697
http://dx.doi.org/10.1186/s13104-023-06454-4
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author Jabbour, Rose Mary
Hallit, Souheil
Saliby, Rita
Baydoun, Abed El Karim
Nakhoul, Nancy
author_facet Jabbour, Rose Mary
Hallit, Souheil
Saliby, Rita
Baydoun, Abed El Karim
Nakhoul, Nancy
author_sort Jabbour, Rose Mary
collection PubMed
description BACKGROUND: The effects of COVID-19 on the organism are still being investigated, especially after the transformation of this virus from a respiratory disease in its first appearance to a multi-organ disease that can affect nearly all systems and organs including the endocrinological system. The objective of the study was to find an association between COVID-19 infection and new onset type 2 diabetes in Lebanese adults. METHODS: A retrospective case–control study (2019–2022) included 200 subjects, 100 cases with new onset diabetes and 100 controls recruited from endocrinology clinics in rural and suburban located regions of Lebanon. Univariate and multivariate logistic regression were performed. RESULTS: Older age (aOR = 1.07; 95% CI 1.03–1.12), higher BMI (aOR = 1.32; 95% CI 1.17–1.48), having been infected with COVID-19 (aOR = 2.38; 95% CI 1.001–5.68) and having a family history of diabetes (aOR = 11.80; 95% CI 4.23–32.87) were significantly associated with higher odds of having new onset type 2 diabetes after adjusting for multiple risk factors. CONCLUSION: In addition to the traditional risk factors for developing type 2 diabetes, a recent COVID-19 infection was associated with the new onset DM in our study. Subsequently screening for diabetes should be strongly recommended for patients post COVID-19 infection. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-023-06454-4.
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spelling pubmed-104395382023-08-20 Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults? Jabbour, Rose Mary Hallit, Souheil Saliby, Rita Baydoun, Abed El Karim Nakhoul, Nancy BMC Res Notes Research Note BACKGROUND: The effects of COVID-19 on the organism are still being investigated, especially after the transformation of this virus from a respiratory disease in its first appearance to a multi-organ disease that can affect nearly all systems and organs including the endocrinological system. The objective of the study was to find an association between COVID-19 infection and new onset type 2 diabetes in Lebanese adults. METHODS: A retrospective case–control study (2019–2022) included 200 subjects, 100 cases with new onset diabetes and 100 controls recruited from endocrinology clinics in rural and suburban located regions of Lebanon. Univariate and multivariate logistic regression were performed. RESULTS: Older age (aOR = 1.07; 95% CI 1.03–1.12), higher BMI (aOR = 1.32; 95% CI 1.17–1.48), having been infected with COVID-19 (aOR = 2.38; 95% CI 1.001–5.68) and having a family history of diabetes (aOR = 11.80; 95% CI 4.23–32.87) were significantly associated with higher odds of having new onset type 2 diabetes after adjusting for multiple risk factors. CONCLUSION: In addition to the traditional risk factors for developing type 2 diabetes, a recent COVID-19 infection was associated with the new onset DM in our study. Subsequently screening for diabetes should be strongly recommended for patients post COVID-19 infection. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13104-023-06454-4. BioMed Central 2023-08-18 /pmc/articles/PMC10439538/ /pubmed/37596697 http://dx.doi.org/10.1186/s13104-023-06454-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Jabbour, Rose Mary
Hallit, Souheil
Saliby, Rita
Baydoun, Abed El Karim
Nakhoul, Nancy
Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults?
title Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults?
title_full Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults?
title_fullStr Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults?
title_full_unstemmed Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults?
title_short Is COVID-19 incriminated in new onset type 2 diabetes mellitus in Lebanese adults?
title_sort is covid-19 incriminated in new onset type 2 diabetes mellitus in lebanese adults?
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439538/
https://www.ncbi.nlm.nih.gov/pubmed/37596697
http://dx.doi.org/10.1186/s13104-023-06454-4
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