ITC-6102RO, a novel B7-H3 antibody-drug conjugate, exhibits potent therapeutic effects against B7-H3 expressing solid tumors

BACKGROUND: The B7-H3 protein, encoded by the CD276 gene, is a member of the B7 family of proteins and a transmembrane glycoprotein. It is highly expressed in various solid tumors, such as lung and breast cancer, and has been associated with limited expression in normal tissues and poor clinical out...

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Detalles Bibliográficos
Autores principales: Shin, Seol Hwa, Ju, Eun Jin, Park, Jin, Ko, Eun Jung, Kwon, Mi Ri, Lee, Hye Won, Son, Ga Won, Park, Yun-Yong, Kim, Yeon Joo, Song, Si Yeol, Lee, Sangkwang, Seo, Beom Seok, Song, Jin-A, Lim, Sangbin, Jung, Doohwan, Kim, Sunyoung, Lee, Hyangsook, Park, Seok Soon, Jeong, Seong-Yun, Choi, Eun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439577/
https://www.ncbi.nlm.nih.gov/pubmed/37596639
http://dx.doi.org/10.1186/s12935-023-02991-x

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