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Antifungal effects of eugenol on Candida albicans adherence to denture polymers
BACKGROUND: The study’s objective is to assess the adherence of C. albicans in different types of denture polymers and the effectiveness of eugenol and commercialized denture cleansers in the removal of C. albicans. Three types of denture base polymers (Lucitone(®) 199 (High-Impact PMMA), Impact(®)...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439715/ https://www.ncbi.nlm.nih.gov/pubmed/37601266 http://dx.doi.org/10.7717/peerj.15750 |
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author | Zanul Abidin, Zubaidah Mohd Salleh, Nosizana Himratul-Aznita, Wan Harun Ahmad, Siti Fauzza Lim, Ghee Seong Raja Mohd, Noorhayati Dziaruddin, Nabihah |
author_facet | Zanul Abidin, Zubaidah Mohd Salleh, Nosizana Himratul-Aznita, Wan Harun Ahmad, Siti Fauzza Lim, Ghee Seong Raja Mohd, Noorhayati Dziaruddin, Nabihah |
author_sort | Zanul Abidin, Zubaidah |
collection | PubMed |
description | BACKGROUND: The study’s objective is to assess the adherence of C. albicans in different types of denture polymers and the effectiveness of eugenol and commercialized denture cleansers in the removal of C. albicans. Three types of denture base polymers (Lucitone(®) 199 (High-Impact PMMA), Impact(®) (conventional PMMA) and Eclipse(®) (UDMA)) and two hard denture reline materials (Kooliner(®) and Tokuyama(®) Rebase II Fast) were used in this study. METHODS: Three hundred samples were prepared (6 × 2 mm disc shape) and divided into five groups of denture polymers (n = 60) and further subjected into five treatment groups (Polident(®), Steradent, distilled water, eugenol 5-minutes, and eugenol 10-min). Three samples were extracted from each treatment group for baseline data (n = 12). Baseline data were used to calculate the initial number of C. albicans adherence. A 0.5 ml immersion solution from each specimen was cultured on YPD agar and incubated for 48 h at 37 °C. Visible colonies were counted using a colony counter machine (ROCKER Galaxy 230). RESULTS: The result showed that the denture base polymer significantly affected the initial adherence (p = 0.007). The removal of C. albicans was also considerably affected by the denture base polymers and denture cleansers (p < 0.05). Lucitone(®), Tokuyama(®), and Kooliner(®) denture base polymers immersed for 3 min in eugenol showed the best results of removal. DISCUSSION: This study’s overall results showed that all denture polymers used as denture bases had an effect on C. albicans initial adherence and removal from the denture base, and eugenol is comparable to commercialised denture cleansers in reducing the number of attached C. albicans on denture base polymers. |
format | Online Article Text |
id | pubmed-10439715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104397152023-08-20 Antifungal effects of eugenol on Candida albicans adherence to denture polymers Zanul Abidin, Zubaidah Mohd Salleh, Nosizana Himratul-Aznita, Wan Harun Ahmad, Siti Fauzza Lim, Ghee Seong Raja Mohd, Noorhayati Dziaruddin, Nabihah PeerJ Biochemistry BACKGROUND: The study’s objective is to assess the adherence of C. albicans in different types of denture polymers and the effectiveness of eugenol and commercialized denture cleansers in the removal of C. albicans. Three types of denture base polymers (Lucitone(®) 199 (High-Impact PMMA), Impact(®) (conventional PMMA) and Eclipse(®) (UDMA)) and two hard denture reline materials (Kooliner(®) and Tokuyama(®) Rebase II Fast) were used in this study. METHODS: Three hundred samples were prepared (6 × 2 mm disc shape) and divided into five groups of denture polymers (n = 60) and further subjected into five treatment groups (Polident(®), Steradent, distilled water, eugenol 5-minutes, and eugenol 10-min). Three samples were extracted from each treatment group for baseline data (n = 12). Baseline data were used to calculate the initial number of C. albicans adherence. A 0.5 ml immersion solution from each specimen was cultured on YPD agar and incubated for 48 h at 37 °C. Visible colonies were counted using a colony counter machine (ROCKER Galaxy 230). RESULTS: The result showed that the denture base polymer significantly affected the initial adherence (p = 0.007). The removal of C. albicans was also considerably affected by the denture base polymers and denture cleansers (p < 0.05). Lucitone(®), Tokuyama(®), and Kooliner(®) denture base polymers immersed for 3 min in eugenol showed the best results of removal. DISCUSSION: This study’s overall results showed that all denture polymers used as denture bases had an effect on C. albicans initial adherence and removal from the denture base, and eugenol is comparable to commercialised denture cleansers in reducing the number of attached C. albicans on denture base polymers. PeerJ Inc. 2023-08-16 /pmc/articles/PMC10439715/ /pubmed/37601266 http://dx.doi.org/10.7717/peerj.15750 Text en ©2023 Zanul Abidin et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. |
spellingShingle | Biochemistry Zanul Abidin, Zubaidah Mohd Salleh, Nosizana Himratul-Aznita, Wan Harun Ahmad, Siti Fauzza Lim, Ghee Seong Raja Mohd, Noorhayati Dziaruddin, Nabihah Antifungal effects of eugenol on Candida albicans adherence to denture polymers |
title | Antifungal effects of eugenol on Candida albicans adherence to denture polymers |
title_full | Antifungal effects of eugenol on Candida albicans adherence to denture polymers |
title_fullStr | Antifungal effects of eugenol on Candida albicans adherence to denture polymers |
title_full_unstemmed | Antifungal effects of eugenol on Candida albicans adherence to denture polymers |
title_short | Antifungal effects of eugenol on Candida albicans adherence to denture polymers |
title_sort | antifungal effects of eugenol on candida albicans adherence to denture polymers |
topic | Biochemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439715/ https://www.ncbi.nlm.nih.gov/pubmed/37601266 http://dx.doi.org/10.7717/peerj.15750 |
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