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Giant Cell Tumour of the Small Bones of Hand and Foot

Introduction Giant cell tumor (GCT) or bony tumor mainly involving long bones of arms and legs is very rarely associated with the small bones of hands and feet. Due to its nonspecific signs and symptoms, it is not easy to diagnose based on clinical findings; therefore, histopathological evidence is...

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Autores principales: Patel, Rahul, Parmar, Rahul, Agarwal, Srishty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439728/
https://www.ncbi.nlm.nih.gov/pubmed/37602020
http://dx.doi.org/10.7759/cureus.42197
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author Patel, Rahul
Parmar, Rahul
Agarwal, Srishty
author_facet Patel, Rahul
Parmar, Rahul
Agarwal, Srishty
author_sort Patel, Rahul
collection PubMed
description Introduction Giant cell tumor (GCT) or bony tumor mainly involving long bones of arms and legs is very rarely associated with the small bones of hands and feet. Due to its nonspecific signs and symptoms, it is not easy to diagnose based on clinical findings; therefore, histopathological evidence is required to confirm it. Method A total of 16 patients with positive histopathological bone lesions enriched with giant cells were included in our study. After a complete evaluation of their case records, the required radiological assessment was carried out. Campanacci's method of staging was used to evaluate the advancement of lesions. The Musculoskeletal Tumour Society (MSTS) score was recorded postoperatively. All the patients were followed up for a mean duration of 2.8 years until they were lost to follow-up. Result The result of the current study shows that 62.5% of our patients presented in their twenties and 81.25% of patients came at a reasonably advanced stage. Hand and foot were involved in 1:1 cases. Patients were treated by one of the following options: extended curettage with bone graft or cement, wide excision, or en bloc resection. Phenol, a neoadjuvant, was used in all patients. Two of our patients (6.25%) who underwent curettage with bone graft showed up with recurrence during follow-up - one was then treated with wide excision and the other with amputation. Conclusion Giant cell tumors should undoubtedly be aggressively approached with the goal of preserving limb function while reducing recurrence risk to as minimal as possible. GCT of hand is more aggressive comparatively and should be treated accordingly.
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spelling pubmed-104397282023-08-20 Giant Cell Tumour of the Small Bones of Hand and Foot Patel, Rahul Parmar, Rahul Agarwal, Srishty Cureus Oncology Introduction Giant cell tumor (GCT) or bony tumor mainly involving long bones of arms and legs is very rarely associated with the small bones of hands and feet. Due to its nonspecific signs and symptoms, it is not easy to diagnose based on clinical findings; therefore, histopathological evidence is required to confirm it. Method A total of 16 patients with positive histopathological bone lesions enriched with giant cells were included in our study. After a complete evaluation of their case records, the required radiological assessment was carried out. Campanacci's method of staging was used to evaluate the advancement of lesions. The Musculoskeletal Tumour Society (MSTS) score was recorded postoperatively. All the patients were followed up for a mean duration of 2.8 years until they were lost to follow-up. Result The result of the current study shows that 62.5% of our patients presented in their twenties and 81.25% of patients came at a reasonably advanced stage. Hand and foot were involved in 1:1 cases. Patients were treated by one of the following options: extended curettage with bone graft or cement, wide excision, or en bloc resection. Phenol, a neoadjuvant, was used in all patients. Two of our patients (6.25%) who underwent curettage with bone graft showed up with recurrence during follow-up - one was then treated with wide excision and the other with amputation. Conclusion Giant cell tumors should undoubtedly be aggressively approached with the goal of preserving limb function while reducing recurrence risk to as minimal as possible. GCT of hand is more aggressive comparatively and should be treated accordingly. Cureus 2023-07-20 /pmc/articles/PMC10439728/ /pubmed/37602020 http://dx.doi.org/10.7759/cureus.42197 Text en Copyright © 2023, Patel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Patel, Rahul
Parmar, Rahul
Agarwal, Srishty
Giant Cell Tumour of the Small Bones of Hand and Foot
title Giant Cell Tumour of the Small Bones of Hand and Foot
title_full Giant Cell Tumour of the Small Bones of Hand and Foot
title_fullStr Giant Cell Tumour of the Small Bones of Hand and Foot
title_full_unstemmed Giant Cell Tumour of the Small Bones of Hand and Foot
title_short Giant Cell Tumour of the Small Bones of Hand and Foot
title_sort giant cell tumour of the small bones of hand and foot
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439728/
https://www.ncbi.nlm.nih.gov/pubmed/37602020
http://dx.doi.org/10.7759/cureus.42197
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