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Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report
Pyoderma gangrenosum (PG) is an inflammatory disease characterized by recurrent painful ulcers, eventually leading to cribriform scars. PG is mostly a diagnosis of exclusion with neutrophilic skin infiltration. We present a case of a 35-year-old female patient whose first presentation of PG occurred...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439785/ https://www.ncbi.nlm.nih.gov/pubmed/37602127 http://dx.doi.org/10.7759/cureus.42203 |
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author | Sarwar, Sarosh Sajid, Fatima Wasim, Asad Ullah Waleed, Madeeha Subhan Thada, Pawan Kumar |
author_facet | Sarwar, Sarosh Sajid, Fatima Wasim, Asad Ullah Waleed, Madeeha Subhan Thada, Pawan Kumar |
author_sort | Sarwar, Sarosh |
collection | PubMed |
description | Pyoderma gangrenosum (PG) is an inflammatory disease characterized by recurrent painful ulcers, eventually leading to cribriform scars. PG is mostly a diagnosis of exclusion with neutrophilic skin infiltration. We present a case of a 35-year-old female patient whose first presentation of PG occurred in the first trimester of pregnancy, which recurred after discontinuation of breastfeeding. The patient also had a history of taking prolonged IM and IV analgesics for her chronic migraines. The patient was initially treated with steroids and necessary wound care, during which symptoms remained controlled. However, a year later, the patient presented with an acute flare-up of the disease in her postpartum period, mainly involving her breasts bilaterally. Extensive wound debridement was performed due to the severity of her necrotic ulcers and failure to respond to conservative management, which was followed by partial thickness skin grafting. |
format | Online Article Text |
id | pubmed-10439785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-104397852023-08-20 Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report Sarwar, Sarosh Sajid, Fatima Wasim, Asad Ullah Waleed, Madeeha Subhan Thada, Pawan Kumar Cureus Dermatology Pyoderma gangrenosum (PG) is an inflammatory disease characterized by recurrent painful ulcers, eventually leading to cribriform scars. PG is mostly a diagnosis of exclusion with neutrophilic skin infiltration. We present a case of a 35-year-old female patient whose first presentation of PG occurred in the first trimester of pregnancy, which recurred after discontinuation of breastfeeding. The patient also had a history of taking prolonged IM and IV analgesics for her chronic migraines. The patient was initially treated with steroids and necessary wound care, during which symptoms remained controlled. However, a year later, the patient presented with an acute flare-up of the disease in her postpartum period, mainly involving her breasts bilaterally. Extensive wound debridement was performed due to the severity of her necrotic ulcers and failure to respond to conservative management, which was followed by partial thickness skin grafting. Cureus 2023-07-20 /pmc/articles/PMC10439785/ /pubmed/37602127 http://dx.doi.org/10.7759/cureus.42203 Text en Copyright © 2023, Sarwar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Sarwar, Sarosh Sajid, Fatima Wasim, Asad Ullah Waleed, Madeeha Subhan Thada, Pawan Kumar Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report |
title | Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report |
title_full | Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report |
title_fullStr | Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report |
title_full_unstemmed | Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report |
title_short | Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report |
title_sort | pyoderma gangrenosum precipitated by breast engorgement following lactation discontinuation: a rare case report |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439785/ https://www.ncbi.nlm.nih.gov/pubmed/37602127 http://dx.doi.org/10.7759/cureus.42203 |
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