Cargando…

Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report

Pyoderma gangrenosum (PG) is an inflammatory disease characterized by recurrent painful ulcers, eventually leading to cribriform scars. PG is mostly a diagnosis of exclusion with neutrophilic skin infiltration. We present a case of a 35-year-old female patient whose first presentation of PG occurred...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarwar, Sarosh, Sajid, Fatima, Wasim, Asad Ullah, Waleed, Madeeha Subhan, Thada, Pawan Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439785/
https://www.ncbi.nlm.nih.gov/pubmed/37602127
http://dx.doi.org/10.7759/cureus.42203
_version_ 1785093027272851456
author Sarwar, Sarosh
Sajid, Fatima
Wasim, Asad Ullah
Waleed, Madeeha Subhan
Thada, Pawan Kumar
author_facet Sarwar, Sarosh
Sajid, Fatima
Wasim, Asad Ullah
Waleed, Madeeha Subhan
Thada, Pawan Kumar
author_sort Sarwar, Sarosh
collection PubMed
description Pyoderma gangrenosum (PG) is an inflammatory disease characterized by recurrent painful ulcers, eventually leading to cribriform scars. PG is mostly a diagnosis of exclusion with neutrophilic skin infiltration. We present a case of a 35-year-old female patient whose first presentation of PG occurred in the first trimester of pregnancy, which recurred after discontinuation of breastfeeding. The patient also had a history of taking prolonged IM and IV analgesics for her chronic migraines. The patient was initially treated with steroids and necessary wound care, during which symptoms remained controlled. However, a year later, the patient presented with an acute flare-up of the disease in her postpartum period, mainly involving her breasts bilaterally. Extensive wound debridement was performed due to the severity of her necrotic ulcers and failure to respond to conservative management, which was followed by partial thickness skin grafting.
format Online
Article
Text
id pubmed-10439785
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-104397852023-08-20 Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report Sarwar, Sarosh Sajid, Fatima Wasim, Asad Ullah Waleed, Madeeha Subhan Thada, Pawan Kumar Cureus Dermatology Pyoderma gangrenosum (PG) is an inflammatory disease characterized by recurrent painful ulcers, eventually leading to cribriform scars. PG is mostly a diagnosis of exclusion with neutrophilic skin infiltration. We present a case of a 35-year-old female patient whose first presentation of PG occurred in the first trimester of pregnancy, which recurred after discontinuation of breastfeeding. The patient also had a history of taking prolonged IM and IV analgesics for her chronic migraines. The patient was initially treated with steroids and necessary wound care, during which symptoms remained controlled. However, a year later, the patient presented with an acute flare-up of the disease in her postpartum period, mainly involving her breasts bilaterally. Extensive wound debridement was performed due to the severity of her necrotic ulcers and failure to respond to conservative management, which was followed by partial thickness skin grafting. Cureus 2023-07-20 /pmc/articles/PMC10439785/ /pubmed/37602127 http://dx.doi.org/10.7759/cureus.42203 Text en Copyright © 2023, Sarwar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Sarwar, Sarosh
Sajid, Fatima
Wasim, Asad Ullah
Waleed, Madeeha Subhan
Thada, Pawan Kumar
Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report
title Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report
title_full Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report
title_fullStr Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report
title_full_unstemmed Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report
title_short Pyoderma Gangrenosum Precipitated by Breast Engorgement Following Lactation Discontinuation: A Rare Case Report
title_sort pyoderma gangrenosum precipitated by breast engorgement following lactation discontinuation: a rare case report
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439785/
https://www.ncbi.nlm.nih.gov/pubmed/37602127
http://dx.doi.org/10.7759/cureus.42203
work_keys_str_mv AT sarwarsarosh pyodermagangrenosumprecipitatedbybreastengorgementfollowinglactationdiscontinuationararecasereport
AT sajidfatima pyodermagangrenosumprecipitatedbybreastengorgementfollowinglactationdiscontinuationararecasereport
AT wasimasadullah pyodermagangrenosumprecipitatedbybreastengorgementfollowinglactationdiscontinuationararecasereport
AT waleedmadeehasubhan pyodermagangrenosumprecipitatedbybreastengorgementfollowinglactationdiscontinuationararecasereport
AT thadapawankumar pyodermagangrenosumprecipitatedbybreastengorgementfollowinglactationdiscontinuationararecasereport