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Precision medicine in neurosurgery: The evolving role of theranostics
Theranostics in neurosurgery is a rapidly advancing field of precision medicine that combines diagnostic and therapeutic modalities to optimize patient outcomes. This approach has the potential to provide real-time feedback during therapy and diagnose a condition while simultaneously providing treat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439809/ https://www.ncbi.nlm.nih.gov/pubmed/37601162 http://dx.doi.org/10.36922/itps.417 |
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author | Patel, Drashti Nguyen, Andrew Fleeting, Chance Patel, Anjali B. Mumtaz, Mohammed Lucke-Wold, Brandon |
author_facet | Patel, Drashti Nguyen, Andrew Fleeting, Chance Patel, Anjali B. Mumtaz, Mohammed Lucke-Wold, Brandon |
author_sort | Patel, Drashti |
collection | PubMed |
description | Theranostics in neurosurgery is a rapidly advancing field of precision medicine that combines diagnostic and therapeutic modalities to optimize patient outcomes. This approach has the potential to provide real-time feedback during therapy and diagnose a condition while simultaneously providing treatment. One such form of theranostics is focused ultrasound, which has been found to be effective in inducing neuroablation and neuromodulation and improving the efficacy of chemotherapy drugs by disrupting the blood–brain barrier. Targeted radionuclide therapy, which pairs positron emission tomography tracers with therapeutic effects and imaging modalities, is another promising form of theranostics for neurosurgery. Automated pathology analysis is yet another form of theranostics that can provide real-time feedback during the surgical resection of tumors. Electrical stimulation has also shown promise in optimizing therapies for patients with cerebral palsy. Overall, theranostics is a cost-effective way to optimize medical care for patients in neurosurgery. It is a relatively new field, but the advancements made so far show great promise for improving patient outcomes. |
format | Online Article Text |
id | pubmed-10439809 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
record_format | MEDLINE/PubMed |
spelling | pubmed-104398092023-08-19 Precision medicine in neurosurgery: The evolving role of theranostics Patel, Drashti Nguyen, Andrew Fleeting, Chance Patel, Anjali B. Mumtaz, Mohammed Lucke-Wold, Brandon INNOSC Theranostics Pharmacol Sci Article Theranostics in neurosurgery is a rapidly advancing field of precision medicine that combines diagnostic and therapeutic modalities to optimize patient outcomes. This approach has the potential to provide real-time feedback during therapy and diagnose a condition while simultaneously providing treatment. One such form of theranostics is focused ultrasound, which has been found to be effective in inducing neuroablation and neuromodulation and improving the efficacy of chemotherapy drugs by disrupting the blood–brain barrier. Targeted radionuclide therapy, which pairs positron emission tomography tracers with therapeutic effects and imaging modalities, is another promising form of theranostics for neurosurgery. Automated pathology analysis is yet another form of theranostics that can provide real-time feedback during the surgical resection of tumors. Electrical stimulation has also shown promise in optimizing therapies for patients with cerebral palsy. Overall, theranostics is a cost-effective way to optimize medical care for patients in neurosurgery. It is a relatively new field, but the advancements made so far show great promise for improving patient outcomes. 2023 2023-08-03 /pmc/articles/PMC10439809/ /pubmed/37601162 http://dx.doi.org/10.36922/itps.417 Text en https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License, permitting distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Patel, Drashti Nguyen, Andrew Fleeting, Chance Patel, Anjali B. Mumtaz, Mohammed Lucke-Wold, Brandon Precision medicine in neurosurgery: The evolving role of theranostics |
title | Precision medicine in neurosurgery: The evolving role of theranostics |
title_full | Precision medicine in neurosurgery: The evolving role of theranostics |
title_fullStr | Precision medicine in neurosurgery: The evolving role of theranostics |
title_full_unstemmed | Precision medicine in neurosurgery: The evolving role of theranostics |
title_short | Precision medicine in neurosurgery: The evolving role of theranostics |
title_sort | precision medicine in neurosurgery: the evolving role of theranostics |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439809/ https://www.ncbi.nlm.nih.gov/pubmed/37601162 http://dx.doi.org/10.36922/itps.417 |
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