Cargando…

Precision medicine in neurosurgery: The evolving role of theranostics

Theranostics in neurosurgery is a rapidly advancing field of precision medicine that combines diagnostic and therapeutic modalities to optimize patient outcomes. This approach has the potential to provide real-time feedback during therapy and diagnose a condition while simultaneously providing treat...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Drashti, Nguyen, Andrew, Fleeting, Chance, Patel, Anjali B., Mumtaz, Mohammed, Lucke-Wold, Brandon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439809/
https://www.ncbi.nlm.nih.gov/pubmed/37601162
http://dx.doi.org/10.36922/itps.417
_version_ 1785093032840790016
author Patel, Drashti
Nguyen, Andrew
Fleeting, Chance
Patel, Anjali B.
Mumtaz, Mohammed
Lucke-Wold, Brandon
author_facet Patel, Drashti
Nguyen, Andrew
Fleeting, Chance
Patel, Anjali B.
Mumtaz, Mohammed
Lucke-Wold, Brandon
author_sort Patel, Drashti
collection PubMed
description Theranostics in neurosurgery is a rapidly advancing field of precision medicine that combines diagnostic and therapeutic modalities to optimize patient outcomes. This approach has the potential to provide real-time feedback during therapy and diagnose a condition while simultaneously providing treatment. One such form of theranostics is focused ultrasound, which has been found to be effective in inducing neuroablation and neuromodulation and improving the efficacy of chemotherapy drugs by disrupting the blood–brain barrier. Targeted radionuclide therapy, which pairs positron emission tomography tracers with therapeutic effects and imaging modalities, is another promising form of theranostics for neurosurgery. Automated pathology analysis is yet another form of theranostics that can provide real-time feedback during the surgical resection of tumors. Electrical stimulation has also shown promise in optimizing therapies for patients with cerebral palsy. Overall, theranostics is a cost-effective way to optimize medical care for patients in neurosurgery. It is a relatively new field, but the advancements made so far show great promise for improving patient outcomes.
format Online
Article
Text
id pubmed-10439809
institution National Center for Biotechnology Information
language English
publishDate 2023
record_format MEDLINE/PubMed
spelling pubmed-104398092023-08-19 Precision medicine in neurosurgery: The evolving role of theranostics Patel, Drashti Nguyen, Andrew Fleeting, Chance Patel, Anjali B. Mumtaz, Mohammed Lucke-Wold, Brandon INNOSC Theranostics Pharmacol Sci Article Theranostics in neurosurgery is a rapidly advancing field of precision medicine that combines diagnostic and therapeutic modalities to optimize patient outcomes. This approach has the potential to provide real-time feedback during therapy and diagnose a condition while simultaneously providing treatment. One such form of theranostics is focused ultrasound, which has been found to be effective in inducing neuroablation and neuromodulation and improving the efficacy of chemotherapy drugs by disrupting the blood–brain barrier. Targeted radionuclide therapy, which pairs positron emission tomography tracers with therapeutic effects and imaging modalities, is another promising form of theranostics for neurosurgery. Automated pathology analysis is yet another form of theranostics that can provide real-time feedback during the surgical resection of tumors. Electrical stimulation has also shown promise in optimizing therapies for patients with cerebral palsy. Overall, theranostics is a cost-effective way to optimize medical care for patients in neurosurgery. It is a relatively new field, but the advancements made so far show great promise for improving patient outcomes. 2023 2023-08-03 /pmc/articles/PMC10439809/ /pubmed/37601162 http://dx.doi.org/10.36922/itps.417 Text en https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License, permitting distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Patel, Drashti
Nguyen, Andrew
Fleeting, Chance
Patel, Anjali B.
Mumtaz, Mohammed
Lucke-Wold, Brandon
Precision medicine in neurosurgery: The evolving role of theranostics
title Precision medicine in neurosurgery: The evolving role of theranostics
title_full Precision medicine in neurosurgery: The evolving role of theranostics
title_fullStr Precision medicine in neurosurgery: The evolving role of theranostics
title_full_unstemmed Precision medicine in neurosurgery: The evolving role of theranostics
title_short Precision medicine in neurosurgery: The evolving role of theranostics
title_sort precision medicine in neurosurgery: the evolving role of theranostics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439809/
https://www.ncbi.nlm.nih.gov/pubmed/37601162
http://dx.doi.org/10.36922/itps.417
work_keys_str_mv AT pateldrashti precisionmedicineinneurosurgerytheevolvingroleoftheranostics
AT nguyenandrew precisionmedicineinneurosurgerytheevolvingroleoftheranostics
AT fleetingchance precisionmedicineinneurosurgerytheevolvingroleoftheranostics
AT patelanjalib precisionmedicineinneurosurgerytheevolvingroleoftheranostics
AT mumtazmohammed precisionmedicineinneurosurgerytheevolvingroleoftheranostics
AT luckewoldbrandon precisionmedicineinneurosurgerytheevolvingroleoftheranostics