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Scalable manufacturing of gene-modified human mesenchymal stromal cells with microcarriers in spinner flasks

ABSTRACT: Due to their immunomodulatory properties and in vitro differentiation ability, human mesenchymal stromal cells (hMSCs) have been investigated in more than 1000 clinical trials over the last decade. Multiple studies that have explored the development of gene-modified hMSC-based products are...

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Detalles Bibliográficos
Autores principales:	Couto, Pedro Silva, Stibbs, Dale J., Rotondi, Marco C., Takeuchi, Yasuhiro, Rafiq, Qasim A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Biotechnological Products and Process Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439856/ https://www.ncbi.nlm.nih.gov/pubmed/37470820 http://dx.doi.org/10.1007/s00253-023-12634-w

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