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Metabolic glycan labeling immobilizes dendritic cell membrane and enhances antitumor efficacy of dendritic cell vaccine

Dendritic cell (DC) vaccine was among the first FDA-approved cancer immunotherapies, but has been limited by the modest cytotoxic T lymphocyte (CTL) response and therapeutic efficacy. Here we report a facile metabolic labeling approach that enables targeted modulation of adoptively transferred DCs f...

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Detalles Bibliográficos
Autores principales: Han, Joonsu, Bhatta, Rimsha, Liu, Yusheng, Bo, Yang, Elosegui-Artola, Alberto, Wang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439884/
https://www.ncbi.nlm.nih.gov/pubmed/37598185
http://dx.doi.org/10.1038/s41467-023-40886-7