Cargando…

Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching

Fluorescent labeling of proteins is a powerful tool for probing structure-function relationships with many biosensing applications. Structure-based rules for systematically designing fluorescent biosensors require understanding ligand-mediated fluorescent response mechanisms which can be challenging...

Descripción completa

Detalles Bibliográficos
Autores principales: Allert, Malin J., Kumar, Shivesh, Wang, You, Beese, Lorena S., Hellinga, Homme W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439942/
https://www.ncbi.nlm.nih.gov/pubmed/37598249
http://dx.doi.org/10.1038/s42004-023-00982-7