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Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching
Fluorescent labeling of proteins is a powerful tool for probing structure-function relationships with many biosensing applications. Structure-based rules for systematically designing fluorescent biosensors require understanding ligand-mediated fluorescent response mechanisms which can be challenging...
Autores principales: | Allert, Malin J., Kumar, Shivesh, Wang, You, Beese, Lorena S., Hellinga, Homme W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439942/ https://www.ncbi.nlm.nih.gov/pubmed/37598249 http://dx.doi.org/10.1038/s42004-023-00982-7 |
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