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Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis

Expression of recombinant proteins in plant cells with a “designer” hydroxyproline (Hyp)-O-glycosylated peptide (HypGP), such as tandem repeats of a “Ser-Pro” motif, has been shown to boost the secreted protein yields. However, dramatic secretion and Hyp-O-glycosylation of HypGP-tagged proteins can...

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Detalles Bibliográficos
Autores principales:	Karki, Uddhab, Perez Sanchez, Paula, Chakraborty, Sankalpa, Dickey, Berry, Vargas Ulloa, Jacqueline, Zhang, Ningning, Xu, Jianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439957/ https://www.ncbi.nlm.nih.gov/pubmed/37598266 http://dx.doi.org/10.1038/s41598-023-40723-3

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