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Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review

The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years, the use of these mRNA vaccines has been restricted as they are unstable and their low efficiency in...

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Detalles Bibliográficos
Autores principales: Koppu, Vasavi, Poloju, Deepa, Puvvala, Bhavani, Madineni, Kavitha, Balaji, Shilpa, Sheela, Chandana Muraleedharan Pillai, Manchikanti, Sri Sai Charan, Moon, Satpathy Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440005/
https://www.ncbi.nlm.nih.gov/pubmed/37605738
http://dx.doi.org/10.22088/IJMCM.BUMS.11.3.260
Descripción
Sumario:The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years, the use of these mRNA vaccines has been restricted as they are unstable and their low efficiency in in-vivo delivery. But now, these problems have been solved by recent technological advances. Many studies conducted in animal models and humans demonstrated the good results for the mRNA vaccines. This review provides you a detailed overview of mRNA viral vaccines and considers the current perspectives and future prospects.