Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review

The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years, the use of these mRNA vaccines has been restricted as they are unstable and their low efficiency in...

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Autores principales: Koppu, Vasavi, Poloju, Deepa, Puvvala, Bhavani, Madineni, Kavitha, Balaji, Shilpa, Sheela, Chandana Muraleedharan Pillai, Manchikanti, Sri Sai Charan, Moon, Satpathy Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440005/
https://www.ncbi.nlm.nih.gov/pubmed/37605738
http://dx.doi.org/10.22088/IJMCM.BUMS.11.3.260
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author Koppu, Vasavi
Poloju, Deepa
Puvvala, Bhavani
Madineni, Kavitha
Balaji, Shilpa
Sheela, Chandana Muraleedharan Pillai
Manchikanti, Sri Sai Charan
Moon, Satpathy Moon
author_facet Koppu, Vasavi
Poloju, Deepa
Puvvala, Bhavani
Madineni, Kavitha
Balaji, Shilpa
Sheela, Chandana Muraleedharan Pillai
Manchikanti, Sri Sai Charan
Moon, Satpathy Moon
author_sort Koppu, Vasavi
collection PubMed
description The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years, the use of these mRNA vaccines has been restricted as they are unstable and their low efficiency in in-vivo delivery. But now, these problems have been solved by recent technological advances. Many studies conducted in animal models and humans demonstrated the good results for the mRNA vaccines. This review provides you a detailed overview of mRNA viral vaccines and considers the current perspectives and future prospects.
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spelling pubmed-104400052023-08-21 Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review Koppu, Vasavi Poloju, Deepa Puvvala, Bhavani Madineni, Kavitha Balaji, Shilpa Sheela, Chandana Muraleedharan Pillai Manchikanti, Sri Sai Charan Moon, Satpathy Moon Int J Mol Cell Med Review Article The mRNA vaccines replace our conventional vaccines (live-attenuated and inactivated vaccines) due to their high safety, efficacy, potency and low cost for their manufacturing. Since these many years, the use of these mRNA vaccines has been restricted as they are unstable and their low efficiency in in-vivo delivery. But now, these problems have been solved by recent technological advances. Many studies conducted in animal models and humans demonstrated the good results for the mRNA vaccines. This review provides you a detailed overview of mRNA viral vaccines and considers the current perspectives and future prospects. Babol University of Medical Sciences 2022 /pmc/articles/PMC10440005/ /pubmed/37605738 http://dx.doi.org/10.22088/IJMCM.BUMS.11.3.260 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is published as an open access article distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Review Article
Koppu, Vasavi
Poloju, Deepa
Puvvala, Bhavani
Madineni, Kavitha
Balaji, Shilpa
Sheela, Chandana Muraleedharan Pillai
Manchikanti, Sri Sai Charan
Moon, Satpathy Moon
Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review
title Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review
title_full Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review
title_fullStr Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review
title_full_unstemmed Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review
title_short Current Perspectives and Future Prospects of mRNA Vaccines against Viral Diseases: A Brief Review
title_sort current perspectives and future prospects of mrna vaccines against viral diseases: a brief review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440005/
https://www.ncbi.nlm.nih.gov/pubmed/37605738
http://dx.doi.org/10.22088/IJMCM.BUMS.11.3.260
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