Sternalis Syndrome Misidentified by Multiple Specialties Responding to Botox Treatment: A Case Report and Literature Review

When a clinician, especially one who is specialized in primary care is faced with presenting complaints of deep, sharp, anterior chest pain, the most common differential diagnoses include cardiac and gastrointestinal pain. Musculoskeletal pain is thought of less frequently as a possible root cause. In this case report, we describe the clinical journey of a female athlete who presented with complaints of burning anterior chest pain. Her sternalis syndrome pain was first misdiagnosed as pain of cardiac origin, resulting in pacemaker placement into the patient’s chest. The pain continued, and the same musculoskeletal pain was then presumed to be of gastrointestinal origin due to a previous history of gastroesophageal reflux disease (GERD). As a result of this misidentification, the patient underwent an unnecessary esophageal surgical procedure. Here, we identify the origins of sternalis syndrome pain, what other conditions the pain may be confused with, and how clinicians should not be quick to exclude musculoskeletal pain from a differential diagnosis of acute chest pain. We discuss effective treatments for sternalis syndrome and shed light on this less common cause of anterior chest pain to promote more accurate diagnosis and avoidance of unnecessary surgical interventions.