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Muscle-building supplement β-hydroxy β-methylbutyrate binds to PPARα to improve hippocampal functions in mice

This study underlines the importance of β-hydroxy β-methylbutyrate (HMB), a muscle-building supplement in human, in increasing mouse hippocampal plasticity. Detailed proteomic analyses reveal that HMB serves as a ligand of peroxisome proliferator-activated receptor α (PPARα), a nuclear hormone recep...

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Detalles Bibliográficos
Autores principales:	Paidi, Ramesh K., Raha, Sumita, Roy, Avik, Pahan, Kalipada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440158/ https://www.ncbi.nlm.nih.gov/pubmed/37437568 http://dx.doi.org/10.1016/j.celrep.2023.112717

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