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Endometriosis and dyspareunia: Solving the enigma

INTRODUCTION: Endometriosis is a chronic oestrogen-dependent disease that affects 1 in 10 women of childbearing age. Half of these women have deep dyspareunia. The presence of this symptom has been shown to negatively affect your quality of life. There are few studies in the literature that address...

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Autores principales: Jimenez, Jose Carlos Vilches, Romero, Lucas Lozano, Garcia, Ignacio Brunel, Sanchez, Manuel Lozano, Fernandez, Rodrigo Orozco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440550/
https://www.ncbi.nlm.nih.gov/pubmed/37608962
http://dx.doi.org/10.1016/j.eurox.2023.100224
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author Jimenez, Jose Carlos Vilches
Romero, Lucas Lozano
Garcia, Ignacio Brunel
Sanchez, Manuel Lozano
Fernandez, Rodrigo Orozco
author_facet Jimenez, Jose Carlos Vilches
Romero, Lucas Lozano
Garcia, Ignacio Brunel
Sanchez, Manuel Lozano
Fernandez, Rodrigo Orozco
author_sort Jimenez, Jose Carlos Vilches
collection PubMed
description INTRODUCTION: Endometriosis is a chronic oestrogen-dependent disease that affects 1 in 10 women of childbearing age. Half of these women have deep dyspareunia. The presence of this symptom has been shown to negatively affect your quality of life. There are few studies in the literature that address this issue and its pathophysiology remains poorly understood. MATERIALS AND METHODS: A case-control study has been carried out in order to assess the multi-causality of dyspareunia in patients with endometriosis. All the patients were assessed in a unit specialising in endometriosis and pelvic pain and their disease was staged using high-resolution ultrasound following the criteria of the IDEA group. The patients were divided into two groups, patients with dyspareunia n = 45 (cases) and those without it n = 55 (controls). RESULTS: The only element that was statistically significant in explaining the dyspareunia was the presence of nodules in the retrocervical region with p = 0.000. The odds ratio of dyspareunia in the cases group was 5.3 (95 % CI 2.2–12.5). CONCLUSIONS: Dyspareunia in patients with endometriosis is strongly dependent on the presence of nodules in the retrocervical region, although there are other factors involved that remain unknown, so more studies are still needed to understand and optimally address this symptom.
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spelling pubmed-104405502023-08-22 Endometriosis and dyspareunia: Solving the enigma Jimenez, Jose Carlos Vilches Romero, Lucas Lozano Garcia, Ignacio Brunel Sanchez, Manuel Lozano Fernandez, Rodrigo Orozco Eur J Obstet Gynecol Reprod Biol X Gynaecology INTRODUCTION: Endometriosis is a chronic oestrogen-dependent disease that affects 1 in 10 women of childbearing age. Half of these women have deep dyspareunia. The presence of this symptom has been shown to negatively affect your quality of life. There are few studies in the literature that address this issue and its pathophysiology remains poorly understood. MATERIALS AND METHODS: A case-control study has been carried out in order to assess the multi-causality of dyspareunia in patients with endometriosis. All the patients were assessed in a unit specialising in endometriosis and pelvic pain and their disease was staged using high-resolution ultrasound following the criteria of the IDEA group. The patients were divided into two groups, patients with dyspareunia n = 45 (cases) and those without it n = 55 (controls). RESULTS: The only element that was statistically significant in explaining the dyspareunia was the presence of nodules in the retrocervical region with p = 0.000. The odds ratio of dyspareunia in the cases group was 5.3 (95 % CI 2.2–12.5). CONCLUSIONS: Dyspareunia in patients with endometriosis is strongly dependent on the presence of nodules in the retrocervical region, although there are other factors involved that remain unknown, so more studies are still needed to understand and optimally address this symptom. Elsevier 2023-08-09 /pmc/articles/PMC10440550/ /pubmed/37608962 http://dx.doi.org/10.1016/j.eurox.2023.100224 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Gynaecology
Jimenez, Jose Carlos Vilches
Romero, Lucas Lozano
Garcia, Ignacio Brunel
Sanchez, Manuel Lozano
Fernandez, Rodrigo Orozco
Endometriosis and dyspareunia: Solving the enigma
title Endometriosis and dyspareunia: Solving the enigma
title_full Endometriosis and dyspareunia: Solving the enigma
title_fullStr Endometriosis and dyspareunia: Solving the enigma
title_full_unstemmed Endometriosis and dyspareunia: Solving the enigma
title_short Endometriosis and dyspareunia: Solving the enigma
title_sort endometriosis and dyspareunia: solving the enigma
topic Gynaecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440550/
https://www.ncbi.nlm.nih.gov/pubmed/37608962
http://dx.doi.org/10.1016/j.eurox.2023.100224
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