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Statin-related muscle complications masquerading as soft tissue sarcomas
Musculoskeletal injuries are a known side effect of long-term statin use. These injuries include sudden, atraumatic muscle rupture which can cause extremity hematomas that motivate patients to seek evaluation and physicians to send referrals for oncologic workup. We discuss two cases where malignanc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440552/ https://www.ncbi.nlm.nih.gov/pubmed/37608879 http://dx.doi.org/10.1016/j.tcr.2023.100887 |
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author | Christophel, Elizabeth Ladas, Cassidy Patterson, Francis Lelkes, Valdis |
author_facet | Christophel, Elizabeth Ladas, Cassidy Patterson, Francis Lelkes, Valdis |
author_sort | Christophel, Elizabeth |
collection | PubMed |
description | Musculoskeletal injuries are a known side effect of long-term statin use. These injuries include sudden, atraumatic muscle rupture which can cause extremity hematomas that motivate patients to seek evaluation and physicians to send referrals for oncologic workup. We discuss two cases where malignancy was suspected rather than statin-induced muscle injury. Using these cases as examples, we discuss subtleties between the two diagnoses so that muscle rupture may be considered prior to subspecialist referral. This paper aims to serve as a reminder and guide for physicians who encounter long-term statin users with nonspecific, improving musculoskeletal symptoms and hemorrhagic MRI findings that lack nodular or mass-like enhancements. While referral to orthopedic oncology is always encouraged in cases of uncertainty, it may not always be necessary. |
format | Online Article Text |
id | pubmed-10440552 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104405522023-08-22 Statin-related muscle complications masquerading as soft tissue sarcomas Christophel, Elizabeth Ladas, Cassidy Patterson, Francis Lelkes, Valdis Trauma Case Rep Case Report Musculoskeletal injuries are a known side effect of long-term statin use. These injuries include sudden, atraumatic muscle rupture which can cause extremity hematomas that motivate patients to seek evaluation and physicians to send referrals for oncologic workup. We discuss two cases where malignancy was suspected rather than statin-induced muscle injury. Using these cases as examples, we discuss subtleties between the two diagnoses so that muscle rupture may be considered prior to subspecialist referral. This paper aims to serve as a reminder and guide for physicians who encounter long-term statin users with nonspecific, improving musculoskeletal symptoms and hemorrhagic MRI findings that lack nodular or mass-like enhancements. While referral to orthopedic oncology is always encouraged in cases of uncertainty, it may not always be necessary. Elsevier 2023-08-07 /pmc/articles/PMC10440552/ /pubmed/37608879 http://dx.doi.org/10.1016/j.tcr.2023.100887 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Christophel, Elizabeth Ladas, Cassidy Patterson, Francis Lelkes, Valdis Statin-related muscle complications masquerading as soft tissue sarcomas |
title | Statin-related muscle complications masquerading as soft tissue sarcomas |
title_full | Statin-related muscle complications masquerading as soft tissue sarcomas |
title_fullStr | Statin-related muscle complications masquerading as soft tissue sarcomas |
title_full_unstemmed | Statin-related muscle complications masquerading as soft tissue sarcomas |
title_short | Statin-related muscle complications masquerading as soft tissue sarcomas |
title_sort | statin-related muscle complications masquerading as soft tissue sarcomas |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440552/ https://www.ncbi.nlm.nih.gov/pubmed/37608879 http://dx.doi.org/10.1016/j.tcr.2023.100887 |
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