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The structural basis of hyperpromiscuity in a core combinatorial network of type II toxin–antitoxin and related phage defense systems

Toxin-antitoxin (TA) systems are a large group of small genetic modules found in prokaryotes and their mobile genetic elements. Type II TAs are encoded as bicistronic (two-gene) operons that encode two proteins: a toxin and a neutralizing antitoxin. Using our tool NetFlax (standing for Network-FlaGs...

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Detalles Bibliográficos
Autores principales:	Ernits, Karin, Saha, Chayan Kumar, Brodiazhenko, Tetiana, Chouhan, Bhanu, Shenoy, Aditi, Buttress, Jessica A., Duque-Pedraza, Julián J., Bojar, Veda, Nakamoto, Jose A., Kurata, Tatsuaki, Egorov, Artyom A., Shyrokova, Lena, Johansson, Marcus J. O., Mets, Toomas, Rustamova, Aytan, Džigurski, Jelisaveta, Tenson, Tanel, Garcia-Pino, Abel, Strahl, Henrik, Elofsson, Arne, Hauryliuk, Vasili, Atkinson, Gemma C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440598/ https://www.ncbi.nlm.nih.gov/pubmed/37556498 http://dx.doi.org/10.1073/pnas.2305393120

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