Retrospective study on long-term effects of hormone replacement therapy (HRT) and iron chelation therapy on glucose homeostasis and insulin secretion in female ß- thalassemia major (β-TM) patients with acquired hypogonadotropic- hypogonadism (AHH)

BACKGROUND AND AIM: Hypogonadism and abnormalities of glucose homeostasis, resulting from iron-induced pituitary and pancreatic β-cell dysfunction respectively, are the most frequently reported endocrine abnormalities in patients with ß-thalassemia major (β-TM), also identified as transfusion-depend...

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Detalles Bibliográficos
Autores principales: De Sanctis, Vincenzo, Daar, Shahina, Soliman, Ashraf T, Tzoulis, Ploutarchos, Di Maio, Salvatore, Kattamis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440782/
https://www.ncbi.nlm.nih.gov/pubmed/37539597
http://dx.doi.org/10.23750/abm.v94i4.14631

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