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A primer-independent DNA polymerase-based method for competent whole-genome amplification of intermediate to high GC sequences

Multiple displacement amplification (MDA) has proven to be a useful technique for obtaining large amounts of DNA from tiny samples in genomics and metagenomics. However, MDA has limitations, such as amplification artifacts and biases that can interfere with subsequent quantitative analysis. To overc...

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Detalles Bibliográficos
Autores principales: Ordóñez, Carlos D, Mayoral-Campos, Carmen, Egas, Conceição, Redrejo-Rodríguez, Modesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440786/
https://www.ncbi.nlm.nih.gov/pubmed/37608803
http://dx.doi.org/10.1093/nargab/lqad073