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Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator
BACKGROUND: All cancers harbor somatic mutations in their genomes. In principle, mutations affecting between one and fifty base pairs are generally classified as small mutational events. Conversely, large mutational events affect more than fifty base pairs, and, in most cases, they encompass copy-nu...
Autores principales: | Khandekar, Azhar, Vangara, Raviteja, Barnes, Mark, Díaz-Gay, Marcos, Abbasi, Ammal, Bergstrom, Erik N., Steele, Christopher D., Pillay, Nischalan, Alexandrov, Ludmil B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440861/ https://www.ncbi.nlm.nih.gov/pubmed/37605126 http://dx.doi.org/10.1186/s12864-023-09584-y |
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