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Sodium bicarbonate for the treatment of severe metabolic acidosis with moderate or severe acute kidney injury in the critically ill: protocol for a randomised clinical trial (BICARICU-2)
INTRODUCTION: When both severe metabolic acidemia (pH equal or less than 7.20; PaCO2 equal or less than 45 mm Hg and bicarbonate concentration equal or less than of 20 mmol/L) and moderate-to-severe acute kidney injury are observed, day 28 mortality is approximately 55%–60%. A multiple centre random...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441043/ https://www.ncbi.nlm.nih.gov/pubmed/37591655 http://dx.doi.org/10.1136/bmjopen-2023-073487 |