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Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer

BACKGROUND: Immunotherapy, including adoptive cell therapy (ACT) and immune checkpoint inhibitors (ICIs), has a limited effect in most patients with colorectal cancer (CRC), and the efficacy is further limited in patients with liver metastasis. Lack of antitumor lymphocyte infiltration could be a ma...

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Detalles Bibliográficos
Autores principales:	Quan, Yibo, He, Jie, Zou, Qi, Zhang, Liuxi, Sun, Qihui, Huang, Hongli, Li, Wanglin, Xie, Keping, Wei, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441131/ https://www.ncbi.nlm.nih.gov/pubmed/37597850 http://dx.doi.org/10.1136/jitc-2023-007080

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