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Senescence during early differentiation reduced the chondrogenic differentiation capacity of mesenchymal progenitor cells

Introduction: Mesenchymal stromal/progenitor cells (MSCs) are promising for cartilage cell-based therapies due to their chondrogenic differentiation capacity. However, MSCs can become senescent during in vitro expansion, a state characterized by stable cell cycle arrest, metabolic alterations, and s...

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Detalles Bibliográficos
Autores principales:	Voskamp, Chantal, Koevoet, Wendy J. L. M., Van Osch, Gerjo J. V. M., Narcisi, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441241/ https://www.ncbi.nlm.nih.gov/pubmed/37609111 http://dx.doi.org/10.3389/fbioe.2023.1241338

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