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Approximating conformational Boltzmann distributions with AlphaFold2 predictions
Protein dynamics are intimately tied to biological function and can enable processes such as signal transduction, enzyme catalysis, and molecular recognition. The relative free energies of conformations that contribute to these functional equilibria are evolved for the physiology of the organism. De...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441281/ https://www.ncbi.nlm.nih.gov/pubmed/37609301 http://dx.doi.org/10.1101/2023.08.06.552168 |