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Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Neurons rely on long-range trafficking of synaptic components to form and maintain the complex neural networks that encode the human experience. With a single neuron capable of forming thousands of distinct en passant synapses along its axon, spatially precise delivery of the necessary synaptic comp...

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Detalles Bibliográficos
Autores principales: Aiken, Jayne, Holzbaur, Erika L. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441300/
https://www.ncbi.nlm.nih.gov/pubmed/37609249
http://dx.doi.org/10.1101/2023.08.08.552320