A genome-wide atlas of human cell morphology

A key challenge of the modern genomics era is developing data-driven representations of gene function. Here, we present the first unbiased morphology-based genome-wide perturbation atlas in human cells, containing three genome-scale genotype-phenotype maps comprising >20,000 single-gene CRISPR-Ca...

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Detalles Bibliográficos
Autores principales: Ramezani, Meraj, Bauman, Julia, Singh, Avtar, Weisbart, Erin, Yong, John, Lozada, Maria, Way, Gregory P., Kavari, Sanam L., Diaz, Celeste, Haghighi, Marzieh, Batista, Thiago M., Pérez-Schindler, Joaquín, Claussnitzer, Melina, Singh, Shantanu, Cimini, Beth A., Blainey, Paul C., Carpenter, Anne E., Jan, Calvin H., Neal, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441312/
https://www.ncbi.nlm.nih.gov/pubmed/37609130
http://dx.doi.org/10.1101/2023.08.06.552164

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