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ATRX guards against aberrant differentiation in mesenchymal progenitor cells
Alterations in the tumor suppressor ATRX are recurrently observed in several cancer types including sarcomas, which are mesenchymal neoplasms. ATRX has multiple epigenetic functions including heterochromatin formation and maintenance and regulation of transcription through modulation of chromatin ac...
Autores principales: | Fang, Yan, Barrows, Douglas, Dabas, Yakshi, Carroll, Thomas S, Tap, William D., Nacev, Benjamin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441338/ https://www.ncbi.nlm.nih.gov/pubmed/37609273 http://dx.doi.org/10.1101/2023.08.08.552433 |
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