Adaptor Protein-3 Produces Synaptic Vesicles that Release Phasic Dopamine

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The burst firing of midbrain dopamine neurons releases a phasic dopamine signal that mediates reinforcement learning. At many synapses, however, high firing rates deplete synaptic vesicles (SVs), resulting in synaptic depression that limits release. What accounts for the increased release of dopamin...

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Detalles Bibliográficos
Autores principales: Jain, Shweta, Yee, Andrew G., Maas, James, Gierok, Sarah, Xu, Hongfei, Stansil, Jasmine, Eriksen, Jacob, Nelson, Alexandra, Silm, Katlin, Ford, Christopher P., Edwards, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441354/
https://www.ncbi.nlm.nih.gov/pubmed/37609166
http://dx.doi.org/10.1101/2023.08.07.552338

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