Reversal of Biological Age in Multiple Rat Organs by Young Porcine Plasma Fraction

Young blood plasma is known to confer beneficial effects on various organs in mice and rats. However, it was not known whether plasma from young pigs rejuvenates old rat tissues at the epigenetic level; whether it alters the epigenetic clock, which is a highly accurate molecular biomarker of aging....

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Detalles Bibliográficos
Autores principales: Horvath, Steve, Singh, Kavita, Raj, Ken, Khairnar, Shraddha, Sanghavi, Akshay, Shrivastava, Agnivesh, Zoller, Joseph A., Li, Caesar Z., Herenu, Claudia B., Canatelli-Mallat, Martina, Lehmann, Marianne, Habazin, Siniša, Novokmet, Mislav, Vučković, Frano, Woods, Leah C. Solberg, Martinez, Angel Garcia, Wang, Tengfei, Chiavellini, Priscila, Levine, Andrew J., Chen, Hao, Brooke, Robert T, Gordevicius, Juozas, Lauc, Gordan, Goya, Rodolfo G., Katcher, Harold L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441355/
https://www.ncbi.nlm.nih.gov/pubmed/37609328
http://dx.doi.org/10.1101/2023.08.06.552148

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