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MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins

Cadherin family proteins play a central role in epithelial and endothelial cell-cell adhesion. The dynamic regulation of cell adhesion is achieved in part through endocytic membrane trafficking pathways that modulate cadherin cell surface levels. Here, we define the role for various MARCH family ubi...

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Detalles Bibliográficos
Autores principales: Seo, Tadahiko, Lowery, Anthony M., Xu, Haifang, Giang, William, Troyanovsky, Sergey M., Vincent, Peter A., Kowalczyk, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441400/
https://www.ncbi.nlm.nih.gov/pubmed/37609155
http://dx.doi.org/10.1101/2023.08.10.552739