Illuminating the Function of the Orphan Transporter, SLC22A10 in Humans and Other Primates

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SLC22A10 is classified as an orphan transporter with unknown substrates and function. Here we describe the discovery of the substrate specificity and functional characteristics of SLC22A10. The human SLC22A10 tagged with green fluorescent protein was found to be absent from the plasma membrane, in c...

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Detalles Bibliográficos
Autores principales: Yee, Sook Wah, Ferrández-Peral, Luis, Alentorn, Pol, Fontsere, Claudia, Ceylan, Merve, Koleske, Megan L., Handin, Niklas, Artegoitia, Virginia M., Lara, Giovanni, Chien, Huan-Chieh, Zhou, Xujia, Dainat, Jacques, Zalevsky, Arthur, Sali, Andrej, Brand, Colin M., Capra, John A., Artursson, Per, Newman, John W., Marques-Bonet, Tomas, Giacomini, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441401/
https://www.ncbi.nlm.nih.gov/pubmed/37609337
http://dx.doi.org/10.1101/2023.08.08.552553

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