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Visualizing a two-state conformational ensemble in stem-loop 3 of the transcriptional regulator 7SK RNA
Structural plasticity is integral to RNA function; however, there are currently few methods to quantitatively resolve RNAs that have multiple structural states. NMR spectroscopy is a powerful approach for resolving conformational ensembles but is size-limited. Chemical probing is well-suited for lar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441402/ https://www.ncbi.nlm.nih.gov/pubmed/37609139 http://dx.doi.org/10.1101/2023.08.09.552709 |