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The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1

Within the bloodstream, monocytes must traverse the microvasculature to prevent leukostasis, which is the entrapment of monocytes within the confines of the microvasculature. Using the model cell line, THP-1, and VCAM-1 coated channels to simulate the microvasculature, we demonstrate that monocytes...

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Detalles Bibliográficos
Autores principales: Ullo, Maria F., D’Amico, Anna E., Lavenus, Sandrine B., Logue, Jeremy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441414/
https://www.ncbi.nlm.nih.gov/pubmed/37609240
http://dx.doi.org/10.1101/2023.08.11.553020