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Utilization of 5’-deoxy-nucleosides as Growth Substrates by Extraintestinal Pathogenic E. coli via the Dihydroxyacetone Phosphate Shunt

All organisms utilize S-adenosyl-l-methionine (SAM) as a key co-substrate for methylation of biological molecules, synthesis of polyamines, and radical SAM reactions. When these processes occur, 5’-deoxy-nucleosides are formed as byproducts such as S-adenosyl-l-homocysteine (SAH), 5’-methylthioadeno...

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Detalles Bibliográficos
Autores principales: Huening, Katherine A., Groves, Joshua T., Wildenthal, John A., Tabita, F. Robert, North, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441430/
https://www.ncbi.nlm.nih.gov/pubmed/37609188
http://dx.doi.org/10.1101/2023.08.10.552779