Machine-guided design of synthetic cell type-specific cis-regulatory elements

Cis-regulatory elements (CREs) control gene expression, orchestrating tissue identity, developmental timing, and stimulus responses, which collectively define the thousands of unique cell types in the body. While there is great potential for strategically incorporating CREs in therapeutic or biotech...

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Detalles Bibliográficos
Autores principales: Gosai, SJ, Castro, RI, Fuentes, N, Butts, JC, Kales, S, Noche, RR, Mouri, K, Sabeti, PC, Reilly, SK, Tewhey, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441439/
https://www.ncbi.nlm.nih.gov/pubmed/37609287
http://dx.doi.org/10.1101/2023.08.08.552077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441439/
https://www.ncbi.nlm.nih.gov/pubmed/37609287
http://dx.doi.org/10.1101/2023.08.08.552077

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