Common Allergens and Immune Responses Associated with Allergic Rhinitis in China

Allergic rhinitis (AR) is a chronic allergic disease of the upper respiratory system that affects approximately 10–40% of the global population. Due to the large number of plant pollen allergens with obvious seasonal variations, AR is common in China. AR is primarily caused by the abnormal regulatio...

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Autores principales: Li, Qirong, Zhang, Xinyi, Feng, Qiang, Zhou, Hengzong, Ma, Chaoyang, Lin, Chao, Wang, Dongxu, Yin, Jianmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441643/
https://www.ncbi.nlm.nih.gov/pubmed/37609376
http://dx.doi.org/10.2147/JAA.S420328
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author Li, Qirong
Zhang, Xinyi
Feng, Qiang
Zhou, Hengzong
Ma, Chaoyang
Lin, Chao
Wang, Dongxu
Yin, Jianmei
author_facet Li, Qirong
Zhang, Xinyi
Feng, Qiang
Zhou, Hengzong
Ma, Chaoyang
Lin, Chao
Wang, Dongxu
Yin, Jianmei
author_sort Li, Qirong
collection PubMed
description Allergic rhinitis (AR) is a chronic allergic disease of the upper respiratory system that affects approximately 10–40% of the global population. Due to the large number of plant pollen allergens with obvious seasonal variations, AR is common in China. AR is primarily caused by the abnormal regulation of the immune system. Its pathophysiological mechanism involves a series of immune cells and immune mediators, including cytokines. The present review summarizes the common allergens in China and the complex pathophysiological mechanism of AR. Additionally, host allergen contact, signal transduction, immune cell activation, cytokine release, and a series of inflammatory reactions are described according to their sequence of occurrence.
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spelling pubmed-104416432023-08-22 Common Allergens and Immune Responses Associated with Allergic Rhinitis in China Li, Qirong Zhang, Xinyi Feng, Qiang Zhou, Hengzong Ma, Chaoyang Lin, Chao Wang, Dongxu Yin, Jianmei J Asthma Allergy Review Allergic rhinitis (AR) is a chronic allergic disease of the upper respiratory system that affects approximately 10–40% of the global population. Due to the large number of plant pollen allergens with obvious seasonal variations, AR is common in China. AR is primarily caused by the abnormal regulation of the immune system. Its pathophysiological mechanism involves a series of immune cells and immune mediators, including cytokines. The present review summarizes the common allergens in China and the complex pathophysiological mechanism of AR. Additionally, host allergen contact, signal transduction, immune cell activation, cytokine release, and a series of inflammatory reactions are described according to their sequence of occurrence. Dove 2023-08-17 /pmc/articles/PMC10441643/ /pubmed/37609376 http://dx.doi.org/10.2147/JAA.S420328 Text en © 2023 Li et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Li, Qirong
Zhang, Xinyi
Feng, Qiang
Zhou, Hengzong
Ma, Chaoyang
Lin, Chao
Wang, Dongxu
Yin, Jianmei
Common Allergens and Immune Responses Associated with Allergic Rhinitis in China
title Common Allergens and Immune Responses Associated with Allergic Rhinitis in China
title_full Common Allergens and Immune Responses Associated with Allergic Rhinitis in China
title_fullStr Common Allergens and Immune Responses Associated with Allergic Rhinitis in China
title_full_unstemmed Common Allergens and Immune Responses Associated with Allergic Rhinitis in China
title_short Common Allergens and Immune Responses Associated with Allergic Rhinitis in China
title_sort common allergens and immune responses associated with allergic rhinitis in china
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441643/
https://www.ncbi.nlm.nih.gov/pubmed/37609376
http://dx.doi.org/10.2147/JAA.S420328
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