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Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy

BACKGROUND: A recent study has reported that maternal obesity is linked to placental oxidative damage and premature senescence. NADPH oxidase 4 (NOX4) is massively expressed in adipose tissue, and its induced reactive oxygen species have been found to contribute to cellular senescence. While, whethe...

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Detalles Bibliográficos
Autores principales:	Tao, Yuelan, Chen, Wei, Xu, Hongbing, Xu, Jiacheng, Yang, Huan, Luo, Xin, Chen, Miaomiao, He, Jie, Bai, Yuxiang, Qi, Hongbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441661/ https://www.ncbi.nlm.nih.gov/pubmed/37608820 http://dx.doi.org/10.2147/IJN.S419081

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