Collagen fleece in orthopaedic infections

Collagen fleece is a relatively new development. It represents another option in the battle against infection. It is a cheap, biocompatible, and resorbable local antibiotic delivery mechanism with favorable drug release kinetics and low risk of adverse effects or toxicity. Benefit may be conferred w...

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Detalles Bibliográficos
Autores principales: Ge, Susan M., Harvey, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Meeting Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441674/
https://www.ncbi.nlm.nih.gov/pubmed/37609481
http://dx.doi.org/10.1097/OI9.0000000000000111
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author Ge, Susan M.
Harvey, Edward J.
author_facet Ge, Susan M.
Harvey, Edward J.
author_sort Ge, Susan M.
collection PubMed
description Collagen fleece is a relatively new development. It represents another option in the battle against infection. It is a cheap, biocompatible, and resorbable local antibiotic delivery mechanism with favorable drug release kinetics and low risk of adverse effects or toxicity. Benefit may be conferred when used in contaminated cases. Significantly more research is still needed before the adoption of collagen fleece as the standard of care. However, we can likely conclude that there are no major adverse effects and it can be safely used as an adjunct in addition to conventional therapies for the prophylaxis and treatment of infections.
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spelling pubmed-104416742023-08-22 Collagen fleece in orthopaedic infections Ge, Susan M. Harvey, Edward J. OTA Int Meeting Proceedings Collagen fleece is a relatively new development. It represents another option in the battle against infection. It is a cheap, biocompatible, and resorbable local antibiotic delivery mechanism with favorable drug release kinetics and low risk of adverse effects or toxicity. Benefit may be conferred when used in contaminated cases. Significantly more research is still needed before the adoption of collagen fleece as the standard of care. However, we can likely conclude that there are no major adverse effects and it can be safely used as an adjunct in addition to conventional therapies for the prophylaxis and treatment of infections. Lippincott Williams & Wilkins 2021-06-15 /pmc/articles/PMC10441674/ /pubmed/37609481 http://dx.doi.org/10.1097/OI9.0000000000000111 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Orthopaedic Trauma Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Meeting Proceedings
Ge, Susan M.
Harvey, Edward J.
Collagen fleece in orthopaedic infections
title Collagen fleece in orthopaedic infections
title_full Collagen fleece in orthopaedic infections
title_fullStr Collagen fleece in orthopaedic infections
title_full_unstemmed Collagen fleece in orthopaedic infections
title_short Collagen fleece in orthopaedic infections
title_sort collagen fleece in orthopaedic infections
topic Meeting Proceedings
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441674/
https://www.ncbi.nlm.nih.gov/pubmed/37609481
http://dx.doi.org/10.1097/OI9.0000000000000111
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