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Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis

BACKGROUND: Ferroptosis in alveolar and bronchial epithelial cells is one of the main mechanisms underlying the development of chronic obstructive pulmonary disease (COPD). Sodium pyruvate (NaPyr) is a natural antioxidant in the body, exhibiting anti-inflammatory and antioxidant activities. NaPyr ha...

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Detalles Bibliográficos
Autores principales:	Zhao, Ziwen, Xu, Zhao, Chang, Jingwen, He, Liwei, Zhang, Zijin, Song, Xiaoyu, Hou, Xianbang, Fan, Fangtian, Jiang, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441695/ https://www.ncbi.nlm.nih.gov/pubmed/37605161 http://dx.doi.org/10.1186/s12950-023-00347-w

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