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Disease in the Pld4(thss/thss) Model of Murine Lupus Requires TLR9

Phospholipase D4 (PLD4) is an endolysosomal exonuclease of ssRNA and ssDNA, rather than a phospholipase as its name suggests. Human polymorphisms in the PLD4 gene have been linked by genome-wide association studies to systemic sclerosis, rheumatoid arthritis, and systemic lupus erythematosus. Howeve...

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Detalles Bibliográficos
Autores principales:	Gavin, Amanda L., Blane, Tanya R., Thinnes, Therese C., Gerlt, Emma, Marshak-Rothstein, Ann, Huang, Deli, Nemazee, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2023
Materias:	Innate Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441812/ https://www.ncbi.nlm.nih.gov/pubmed/37555846 http://dx.doi.org/10.4049/immunohorizons.2300058

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