New insights into pathogen-mediated modulation of host RNA splicing

Alternative splicing (AS) regulation of pre-mRNA has been proven to be one of the fundamental layers of plant immune system. How pathogens disrupt plant AS process to suppress plant immunity by secreted effectors remain poorly understood. In the recent study, Gui et al. revealed that a previously id...

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Detalles Bibliográficos
Autores principales: Gao, Chuyun, Dong, Suomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442024/
https://www.ncbi.nlm.nih.gov/pubmed/37676360
http://dx.doi.org/10.1007/s44154-022-00053-2
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author Gao, Chuyun
Dong, Suomeng
author_facet Gao, Chuyun
Dong, Suomeng
author_sort Gao, Chuyun
collection PubMed
description Alternative splicing (AS) regulation of pre-mRNA has been proven to be one of the fundamental layers of plant immune system. How pathogens disrupt plant AS process to suppress plant immunity by secreted effectors remain poorly understood. In the recent study, Gui et al. revealed that a previously identified effector PSR1 of Phytophthora interferes with host RNA splicing machinery to modulate small RNA biogenesis, leading to compromised plant immunity. The study provided a novel insight into the importance of AS process during pathogen-host interactions.
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spelling pubmed-104420242023-08-28 New insights into pathogen-mediated modulation of host RNA splicing Gao, Chuyun Dong, Suomeng Stress Biol Highlights Alternative splicing (AS) regulation of pre-mRNA has been proven to be one of the fundamental layers of plant immune system. How pathogens disrupt plant AS process to suppress plant immunity by secreted effectors remain poorly understood. In the recent study, Gui et al. revealed that a previously identified effector PSR1 of Phytophthora interferes with host RNA splicing machinery to modulate small RNA biogenesis, leading to compromised plant immunity. The study provided a novel insight into the importance of AS process during pathogen-host interactions. Springer Nature Singapore 2022-08-15 /pmc/articles/PMC10442024/ /pubmed/37676360 http://dx.doi.org/10.1007/s44154-022-00053-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Highlights
Gao, Chuyun
Dong, Suomeng
New insights into pathogen-mediated modulation of host RNA splicing
title New insights into pathogen-mediated modulation of host RNA splicing
title_full New insights into pathogen-mediated modulation of host RNA splicing
title_fullStr New insights into pathogen-mediated modulation of host RNA splicing
title_full_unstemmed New insights into pathogen-mediated modulation of host RNA splicing
title_short New insights into pathogen-mediated modulation of host RNA splicing
title_sort new insights into pathogen-mediated modulation of host rna splicing
topic Highlights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442024/
https://www.ncbi.nlm.nih.gov/pubmed/37676360
http://dx.doi.org/10.1007/s44154-022-00053-2
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