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Potential of nanoemulsions for accelerated wound healing: innovative strategies

Wounds represent various significant health concerns for patients and also contribute major costs to healthcare systems. Wound healing comprises of overlapped and various coordinated steps such as homeostasis, inflammation, proliferation, and remodeling. In response to the failure of many strategies...

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Autores principales: Chhabra, Jatin, Chopra, Hitesh, Pahwa, Rakesh, Raina, Neha, Wadhwa, Karan, Saini, Swati, Negi, Poonam, Gupta, Madhu, Singh, Inderbir, Dureja, Harish, Emran, Talha Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442146/
https://www.ncbi.nlm.nih.gov/pubmed/37158143
http://dx.doi.org/10.1097/JS9.0000000000000460
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author Chhabra, Jatin
Chopra, Hitesh
Pahwa, Rakesh
Raina, Neha
Wadhwa, Karan
Saini, Swati
Negi, Poonam
Gupta, Madhu
Singh, Inderbir
Dureja, Harish
Emran, Talha Bin
author_facet Chhabra, Jatin
Chopra, Hitesh
Pahwa, Rakesh
Raina, Neha
Wadhwa, Karan
Saini, Swati
Negi, Poonam
Gupta, Madhu
Singh, Inderbir
Dureja, Harish
Emran, Talha Bin
author_sort Chhabra, Jatin
collection PubMed
description Wounds represent various significant health concerns for patients and also contribute major costs to healthcare systems. Wound healing comprises of overlapped and various coordinated steps such as homeostasis, inflammation, proliferation, and remodeling. In response to the failure of many strategies in delivering intended results including wound closure, fluid loss control, and exhibiting properties such as durability, targeted delivery, accelerated action, along with histocompatibility, numerous nanotechnological advances have been introduced. To understand the magnitude of wound therapy, this systematic and updated review discussing the effectiveness of nanoemulsions has been undertaken. This review portrays mechanisms associated with wound healing, factors for delayed wound healing, and various technologies utilized to treat wounds effectively. While many strategies are available, nanoemulsions have attracted the tremendous attention of scientists globally for the research in wound therapy due to their long-term thermodynamic stability and bioavailability. Nanoemulsions not only aid in tissue repair, but are also considered as an excellent delivery system for various synthetic and natural actives. Nanotechnology provides several pivotal benefits in wound healing, including improved skin permeation, controlled release, and stimulation of fibroblast cell proliferation. The significant role of nanoemulsions in improved wound healing along with their preparation techniques has also been highlighted with special emphasis on mechanistic insights. This article illustrates recent research advancements for the utilization of nanoemulsions in wound treatment. An adequate literature search has been conducted using the keywords ‘Nanoemulsions in wound healing’, ‘Wound therapy and nanoemulsions’, ‘Herbal actives in wound therapy’, ‘Natural oils and wounds treatment’ etc., from PubMed, Science Direct, and Google Scholar databases. Referred and original publications in the English language accessed till April 2022 has been included, whereas nonEnglish language papers, unpublished data, and nonoriginal papers were excluded from the study.
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spelling pubmed-104421462023-08-22 Potential of nanoemulsions for accelerated wound healing: innovative strategies Chhabra, Jatin Chopra, Hitesh Pahwa, Rakesh Raina, Neha Wadhwa, Karan Saini, Swati Negi, Poonam Gupta, Madhu Singh, Inderbir Dureja, Harish Emran, Talha Bin Int J Surg Reviews Wounds represent various significant health concerns for patients and also contribute major costs to healthcare systems. Wound healing comprises of overlapped and various coordinated steps such as homeostasis, inflammation, proliferation, and remodeling. In response to the failure of many strategies in delivering intended results including wound closure, fluid loss control, and exhibiting properties such as durability, targeted delivery, accelerated action, along with histocompatibility, numerous nanotechnological advances have been introduced. To understand the magnitude of wound therapy, this systematic and updated review discussing the effectiveness of nanoemulsions has been undertaken. This review portrays mechanisms associated with wound healing, factors for delayed wound healing, and various technologies utilized to treat wounds effectively. While many strategies are available, nanoemulsions have attracted the tremendous attention of scientists globally for the research in wound therapy due to their long-term thermodynamic stability and bioavailability. Nanoemulsions not only aid in tissue repair, but are also considered as an excellent delivery system for various synthetic and natural actives. Nanotechnology provides several pivotal benefits in wound healing, including improved skin permeation, controlled release, and stimulation of fibroblast cell proliferation. The significant role of nanoemulsions in improved wound healing along with their preparation techniques has also been highlighted with special emphasis on mechanistic insights. This article illustrates recent research advancements for the utilization of nanoemulsions in wound treatment. An adequate literature search has been conducted using the keywords ‘Nanoemulsions in wound healing’, ‘Wound therapy and nanoemulsions’, ‘Herbal actives in wound therapy’, ‘Natural oils and wounds treatment’ etc., from PubMed, Science Direct, and Google Scholar databases. Referred and original publications in the English language accessed till April 2022 has been included, whereas nonEnglish language papers, unpublished data, and nonoriginal papers were excluded from the study. Lippincott Williams & Wilkins 2023-05-09 /pmc/articles/PMC10442146/ /pubmed/37158143 http://dx.doi.org/10.1097/JS9.0000000000000460 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (https://creativecommons.org/licenses/by/4.0/) (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Reviews
Chhabra, Jatin
Chopra, Hitesh
Pahwa, Rakesh
Raina, Neha
Wadhwa, Karan
Saini, Swati
Negi, Poonam
Gupta, Madhu
Singh, Inderbir
Dureja, Harish
Emran, Talha Bin
Potential of nanoemulsions for accelerated wound healing: innovative strategies
title Potential of nanoemulsions for accelerated wound healing: innovative strategies
title_full Potential of nanoemulsions for accelerated wound healing: innovative strategies
title_fullStr Potential of nanoemulsions for accelerated wound healing: innovative strategies
title_full_unstemmed Potential of nanoemulsions for accelerated wound healing: innovative strategies
title_short Potential of nanoemulsions for accelerated wound healing: innovative strategies
title_sort potential of nanoemulsions for accelerated wound healing: innovative strategies
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442146/
https://www.ncbi.nlm.nih.gov/pubmed/37158143
http://dx.doi.org/10.1097/JS9.0000000000000460
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