Replication dynamics identifies the folding principles of the inactive X chromosome

Chromosome-wide late replication is an enigmatic hallmark of the inactive X chromosome (Xi). How it is established and what it represents remains obscure. By single-cell DNA replication sequencing, here we show that the entire Xi is reorganized to replicate rapidly and uniformly in late S-phase duri...

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Detalles Bibliográficos
Autores principales: Poonperm, Rawin, Ichihara, Saya, Miura, Hisashi, Tanigawa, Akie, Nagao, Koji, Obuse, Chikashi, Sado, Takashi, Hiratani, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442229/
https://www.ncbi.nlm.nih.gov/pubmed/37563439
http://dx.doi.org/10.1038/s41594-023-01052-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442229/
https://www.ncbi.nlm.nih.gov/pubmed/37563439
http://dx.doi.org/10.1038/s41594-023-01052-1

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