Evaluating the role of the nuclear microenvironment in gene function by population-based modeling

The nuclear folding of chromosomes relative to nuclear bodies is an integral part of gene function. Here, we demonstrate that population-based modeling—from ensemble Hi-C data—provides a detailed description of the nuclear microenvironment of genes and its role in gene function. We define the microe...

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Detalles Bibliográficos
Autores principales: Yildirim, Asli, Hua, Nan, Boninsegna, Lorenzo, Zhan, Yuxiang, Polles, Guido, Gong, Ke, Hao, Shengli, Li, Wenyuan, Zhou, Xianghong Jasmine, Alber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442234/
https://www.ncbi.nlm.nih.gov/pubmed/37580627
http://dx.doi.org/10.1038/s41594-023-01036-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442234/
https://www.ncbi.nlm.nih.gov/pubmed/37580627
http://dx.doi.org/10.1038/s41594-023-01036-1

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