Cancer stem cell immunoediting by IFNγ

The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progressio...

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Detalles Bibliográficos
Autores principales: Galassi, Claudia, Galluzzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442329/
https://www.ncbi.nlm.nih.gov/pubmed/37604810
http://dx.doi.org/10.1038/s41419-023-06079-2
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author Galassi, Claudia
Galluzzi, Lorenzo
author_facet Galassi, Claudia
Galluzzi, Lorenzo
author_sort Galassi, Claudia
collection PubMed
description The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy.
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spelling pubmed-104423292023-08-23 Cancer stem cell immunoediting by IFNγ Galassi, Claudia Galluzzi, Lorenzo Cell Death Dis Comment The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy. Nature Publishing Group UK 2023-08-21 /pmc/articles/PMC10442329/ /pubmed/37604810 http://dx.doi.org/10.1038/s41419-023-06079-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Galassi, Claudia
Galluzzi, Lorenzo
Cancer stem cell immunoediting by IFNγ
title Cancer stem cell immunoediting by IFNγ
title_full Cancer stem cell immunoediting by IFNγ
title_fullStr Cancer stem cell immunoediting by IFNγ
title_full_unstemmed Cancer stem cell immunoediting by IFNγ
title_short Cancer stem cell immunoediting by IFNγ
title_sort cancer stem cell immunoediting by ifnγ
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442329/
https://www.ncbi.nlm.nih.gov/pubmed/37604810
http://dx.doi.org/10.1038/s41419-023-06079-2
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