The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication

African swine fever virus (ASFV) is a lethal animal pathogen that enters its host cells through endocytosis. So far, host factors specifically required for ASFV replication have been barely identified. In this study a genome-wide CRISPR/Cas9 knockout screen in porcine cells indicated that the genes...

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Detalles Bibliográficos
Autores principales: Pannhorst, Katrin, Carlson, Jolene, Hölper, Julia E., Grey, Finn, Baillie, John Kenneth, Höper, Dirk, Wöhnke, Elisabeth, Franzke, Kati, Karger, Axel, Fuchs, Walter, Mettenleiter, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442341/
https://www.ncbi.nlm.nih.gov/pubmed/37604847
http://dx.doi.org/10.1038/s41598-023-36788-9

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