Targeting SphK1/2 by SKI-178 inhibits prostate cancer cell growth

Sphingosine kinases (SphK), including SphK1 and SphK2, are important enzymes promoting progression of prostate cancer. SKI-178 is a novel and highly potent SphK1/2 dual inhibitor. We here tested the potential anti-prostate cancer cell activity of SKI-178. Bioinformatics analyses and results from loc...

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Detalles Bibliográficos
Autores principales: Jin, Lu, Zhu, Jin, Yao, Linya, Shen, Gang, Xue, Bo-xin, Tao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442381/
https://www.ncbi.nlm.nih.gov/pubmed/37604912
http://dx.doi.org/10.1038/s41419-023-06023-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442381/
https://www.ncbi.nlm.nih.gov/pubmed/37604912
http://dx.doi.org/10.1038/s41419-023-06023-4

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